This guide examines the use of polygraph tests and other truth-telling devices (sometimes called “lie-detector tests”) in sexual assault investigations. It is meant to support the Violence Against Women Act and Department of Justice Reauthorization Act of 2005 (VAWA 2005) provision that truth-telling devices must not be used with sexual assault victims as a condition of charging or prosecution of an offense. This guide examines special issues relevant to using truth-telling devices with sexual assault victims. Legislative and judicial actions that have been taken as a result of this debate will also be discussed. Victim advocates, law enforcement officers, and policy makers may use this guide to develop policies, practices, and procedures and to improve collaborations regarding the use of truth-telling devices as the VAWA 2005 provision is adopted across the United States.