Little is known about the national prevalence of sexual violence, stalking, and intimate partner violence among gay, lesbian, and bisexual women and men in the United States. Information at a national level focusing on these types of interpersonal violence based on the sexual orientation of U.S. adults has not been previously available. The National Intimate Partner and Sexual Violence Survey (NISVS) is an ongoing, nationally representative survey that collects information about experiences of sexual violence and stalking by any perpetrator and intimate partner violence among English and/or Spanish-speaking women and men aged 18 years or older in the United States. This report presents information based on respondents’ self-reported sexual orientation and their lifetime victimization experiences of sexual violence, stalking, and violence by an intimate partner. The findings in this report are for 2010, the first year of NISVS data collection, and are based on complete interviews. Complete interviews were obtained from 16,507 adults (9,086 women and 7,421 men). Prevalence estimates for some types of violence for particular groups were too small to produce reliable estimates and, therefore, are not reported.